Muscarinic M2 and M4 receptor antagonist
- Catalog number: NT1140
- Alternate name: (±)-AFDX-384, BIBN-161
- Molar activity: 80-100 Ci/mmol; 3.0-3.7 TBq/mmol
- Concentration: 1.0 mCi/mL
- CAS Number (Parent): 118290-26-9, 118290-27-0
- Storage conditions: -20°C, in ethanol
- Stability: Under investigation
- Notes: Shipped on dry ice. To inquire about the current price of this product, please mail us your inquiry below.
References
- ”Autoradiography of 3H-pirenzepine and 3H-AFDX-384 in Mouse Brain Regions: Possible Insights into M1, M2, and M4 Muscarinic Receptors Distribution” P. Valuskova, V. Farar, S. Forczek, I. Krizova and J. Myslivecek (2018) Frontiers in Pharmacology 9: 124.
- ”Binding of [3H]AF-DX 384 to cloned and native muscarinic receptors” J. H. Miller, V. A. Gibson and M. McKinney (1991) Journal of Pharmacology and Experimental Therapeutics 259 (2): 601-607.
- “M2 Receptor Binding of the Selective Antagonist AF-DX 384: Possible Involvement of the Common Allosteric Site” C. Tränkle, I. Andresen, G. Lambrecht and K. Mohr (1998) Molecular Pharmacology 53: 304–312.
